Автор Каталог статей Ниацин
Yang X, Mei S, Niu H, Li J. Nicotinic acid impairs assembly of leading edge in glioma cells. Oncol Rep. 2017 Aug; 38 (2):829-836. [PMC free article : PMC5562096 ] [PubMed : 28656206 ]
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© 2024 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. See additional information.
© 2024 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. See additional information.
Niacin Dosage
Everyone needs a certain amount of niacin from food or supplements for the body to function normally. This amount is called the dietary reference intake (DRI), a term that is replacing the older and more familiar RDA (recommended dietary allowance). For niacin, the DRIs vary with age and other factors and are given in milligrams of niacin equivalents:
- Children: 2-16 milligrams daily, depending on age
- Men, or those assigned male at birth (AMAB): 16 milligrams daily
- Women, or those assigned female at birth (AFAB): 14 milligrams daily
- If pregnant: 18 milligrams daily
- If breastfeeding: 17 milligrams daily
- Maximum daily intake for adults of all ages: 35 milligrams daily
Most people can get the niacin they need by eating a healthy diet. If your doctor prescribes niacin, you might want to take it with food. This can prevent upset stomach.
To reduce flushing — a harmless but uncomfortable side effect of niacin that describes redness and warmth in the face and neck — your doctor might recommend taking niacin along with aspirin and avoiding alcohol and spicy foods.
Since niacin can be used in different ways, talk to your doctor about the best dosage for you.
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Contraindications
Contraindications to niacin include the following conditions:
Patients with active peptic ulcer disease
Patients who have active liver disease or present with unexplained and persistent elevations in hepatic transaminases
Patients with hypersensitivity to niacin or any component of this medication
Patients with arterial bleeding
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НИАЦИН ПРЕДОЗИРАНЕ
Когато се включат продукти, богати на B3, предозирането и нежеланите реакции са изключени. Само хора, приемащи лекарства на базата на витамин РР, могат да се сблъскат с този проблем. С увеличаване на препоръчителната доза се развива депресивно състояние, появяват се замайване, сърбеж по кожата и фалшиви тактилни усещания (парестезия). Може да се появи мускулна болка и дисфункция на сърдечно-съдовата система („срив“ на кръвното налягане, аритмия).
Честите нежелани реакции включват:
- разширяване на кръвоносните съдове на шията, лицето и гърдите;
- стомашни разстройства, гадене и повръщане;
- повишаване на концентрацията на кръвната захар.
Някои хора изпитват замъглено зрение и повишени нива на пикочна киселина, което води до развитие на подагра. При приема на ниацин се препоръчва да се следи състоянието на черния дроб, за да се изключи възможна дисфункция.
Источники:
https://www.healthline.com/health/beauty-skin-care/niacinamide&rut=1c9792d164015ace5b5f8f1eeb10f4cbca49b5975f8c2d850da7eb16d1fd04ae
https://www.healthline.com/nutrition/niacin-benefits&rut=4ec3c314277819c69b375502ef6d4a329a4263015daae7488da85cca175198ff
https://www.webmd.com/diet/supplement-guide-niacin&rut=a92d6986bb477a03677c74d997d48a1c02d42593029e385e32035a832b78aade
https://cross.expert/sportivnoe-pitanie/vitaminy/niacin.html&rut=23736a20b4ec182405bc76da6fdb14d720b4669a84e47341bdf34da89ec435cb
https://lpi.oregonstate.edu/mic/vitamins/niacin&rut=858849a68c38e97ed49d03ab3d0637fe7bc7455d2640f07f9ffdcc956d2cebad
https://www.ncbi.nlm.nih.gov/books/NBK541036/&rut=6cf1f8673e0e0a66d1304bbf90587208be48dc70682e78d5bafd307c78d06ec0
https://dietdo.ru/niacin.html&rut=e42fd45c57df8bf5051434f66f72635320bc577617e0fa8b6edea79f116c75a3
https://biovital.bg/blog/niacin-polzi-protivopokazaniya-i-hrani-v-koito-se-sadarja&rut=1f8bcecf8a82010384a255bb8f2b5917fb1b96934e1dcd3831fcd5f8ba3852b4